Conditions

Eclampsia is characterised by induced high blood pressure with seizures unrelated to epilepsy or other brain disorders or conditions. It is unique to pregnancy.

What is eclampsia?

  • The word eclampsia comes from the Greek word "eklampsis" = "a shining forth" / "bolt from the blue"
  • Eclampsia is characterised by induced high blood pressure with seizures unrelated to epilepsy or other brain disorders or conditions. It is unique to pregnancy.
  • Eclampsia may be the final and most severe phase of pre-eclampsia, or it can occur without pre-eclampsia symptoms.
  • Eclampsia can occur before (antepartum,) during (intrapartum) or up to 48 hours after delivery of the baby (postpartum).
  • Eclampsia is dangerous and must be treated immediately to avoid potentially dangerous complications.

Causes of eclampsia

  • The cause of eclampsia cannot really be explained.
  • Factors that could increase a woman's risk of getting eclampsia:
    • undetected high blood pressure (chronic or gestational)
    • pre-eclampsia left untreated,
    • pre-eclampsia never detected and
    • severe cases of pre-eclampsia (Although eclampsia is more likely to occur in severe cases of pre-eclampsia, it can also occur in mild cases)
  • There is not a definite way to predict which women with pre-eclampsia will get eclampsia

Symptoms and signs of eclampsia

  • Eclampsia is characterised by convulsions (seizures/fits) and disseminated intravascular coagulation (DIC) which affects the liver, kidneys, brain, heart and placenta.
  • Other symptoms:
    • severe headaches
    • hyperreflexia - overactive or over-responsive reflexes.
    • severe agitation
    • unconsciousness
    • muscle aches and pain
    • blind or partially blind areas in the field of vision. White spots are sometimes evident during the aura of a migraine headache.

How is eclampsia diagnosed?

  • High blood pressure and the presence of seizures or coma are the only symptoms required for diagnosis.
  • Any pregnant woman with high blood pressure who has a seizure that can't be attributed to some other cause can be diagnosed with eclampsia.

How is eclampsia treated?

  • A woman with eclampsia is usually in hospital when seizures occur and if she is not, due to the nature of the sudden onset of the condition, unforeseen or socio-economical circumstances or a home birth, she should get to hospital as soon as possible.
  • Delivery of the baby and placenta is usually the treatment of choice for eclampsia in a pregnancy over 28 weeks. For pregnancies less than 24 weeks, the start of labour is recommended, although the baby may not survive.
  • Magnesium sulphate might be given to prevent and s top seizures when they are occurring. It is an anticonvulsant drug and is safe for both the mother and the baby.

What is the prognosis?

  • If pregnancy is prolonged and eclampsia is left untreated, it can result in the death of mother and baby.
  • Eclampsia can cause the mother to go into a coma and can cause brain damage.
  • It can lead to postpartum health issues, such as chronic high blood pressure and liver or kidney problems.
  • During a seizure, mother and baby are at risk of being deprived of oxygen.
  • In addition, the high blood pressure may cause the placenta to begin to separate from the wall of the uterus, called a placenta abruptio.
  • The above-mentioned outcome is rare and most women make a full recovery from eclampsia

How can eclampsia be prevented?

  • There is no known prevention of eclampsia.
  • Some measures can be taken to ensure early detection of pregnancy-induced high blood pressure/increased chronic high blood pressure / gestational hypertension and pre-eclampsia:
    • Start with your antenatal visits to your doctor as soon as you can in your pregnancy.
    • Never miss an appointment.
    • Make sure you are monitored more frequently if your blood pressure is raised.
    • Always report any worrying signs or symptoms to your doctor and do not allow him or her to dismiss you without first checking your blood pressure and urine.